Applications are invited for a postdoctoral position to work on the
structure determination of rhomboid intramembrane proteases critical
in cell signaling pathways. These proteases have been linked to human
disorders such as hereditary blindness and breast cancer. Our aim is
to understand the molecular interactions with their substrates,
setting the stage for rational design of novel inhibitors. We seek an
enthusiastic candidate experienced in macromolecular crystallography
Experience with membrane protein biochemistry would be an asset. In
addition, the successful candidate should be well-versed in one or
more of the following areas: molecular biology, protein purification,
crystallization, or membrane protein & lipid biochemistry.
This is an opportunity to join a lab experienced in the expression and
crystallization of membrane proteins (See PNAS (2007) 104(3):750-4,
and Science, (2003). 301:616-620). The University of Alberta, located
in Edmonton, Alberta (Canada), is home to a large and interactive
community of biomedical scientists http://www.med.ualberta.ca/ ;
support and facilities for structural biology are excellent. Our
department provides interaction with numerous crystallographers. A
newly commissioned synchrotron facility is located a short drive away.
In addition, the membrane protein research group provides a dedicated
forum for membrane protein research at the University of Alberta
(http://www.mprg.med.ualberta.ca/index.php ).
Edmonton, having a population of over 1 million, offers a cosmopolitan
environment with world class performing arts, sports, culinary and
recreational opportunities. In addition, the citys proximity to the
Rocky Mountains including the towns of Jasper and Banff is an
additional bonus.
Salary is commensurate with training and experience at the CIHR
standard rates. A medical and dental benefit package is included with
salary. The University of Alberta hires on the basis of merit. We are
committed to the principle of equity in employment. We welcome
diversity and encourage applications from all qualified women and men,
including persons with disabilities, members of visible minorities,
and Aboriginal persons. The records arising from this competition will
be managed in accordance with provisions of the Alberta Freedom of
Information and Protection of Privacy Act (FOIPP).
Please direct cv's or inquiries to Dr. M. Joanne Lemieux at the
following email address: [email protected].
**********************************
M. Joanne Lemieux, Ph.D.
Assistant Professor
Department of Biochemistry
Medical Science Bldg.
Office 4-53
Lab 4-51
University of Alberta
Edmonton AB, T6G 2H7
office phone: 780-492-3586
lab phone: 780-492-3465
fax: 780-492-0886
Lab web page:
http://xray.biochem.ualberta.ca/~joanne/
Membrane protein research group:
http://www.mprg.med.ualberta.ca/index.php
