A postdoctoral position is available in the laboratory of Bert van den Berg at UMass Medical School, Worcester (MA), to work on a NIH-funded project investigating the mechanism by which hydrophobic molecules, such as toxic xenobiotics, cross the bacterial outer membrane. The focus of the project will be on establishing in vivo transport assays for (mono) aromatic hydrocarbons, and the purification, crystallization and structure determination of FadL homologues from biodegrading bacteria. In addition, channel-substrate complexes and site-directed mutants of the toluene channels TodX and TbuX will be subjected to structural studies. For more information please see Hearn et al., Nature 1 Feb 2009, and Hearn et al., PNAS 105, 8601-8606 (2008), or contact me directly. We are looking for a dedicated and enthusiastic person with a strong background in molecular biology. Experience with cloning in Pseudomonas species would be ideal. Experience in membrane protein biochemistry and X-ray crystallography would be advantageous, but is not required. Please send applications and the names of two or three references to: bert.vandenb...@umassmed.edu. Bert van den Berg University of Massachusetts Medical School Program in Molecular Medicine Biotech II, 373 Plantation Street, Suite 115 Worcester MA 01605 Phone: 508 856 1201 (office); 508 856 1211 (lab) e-mail: bert.vandenb...@umassmed.edu http://www.umassmed.edu/pmm/faculty/vandenberg.cfm
________________________________ From: CCP4 bulletin board on behalf of Peer Mittl Sent: Tue 2/24/2009 7:26 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Open Post-Doc and technician positions Applications are invited for four positions at various levels at the University of Zürich (Switzerland). Currently there are four vacant positions at the postdoctoral and research assistant levels (2 Post-Docs and 2 research assistants) in the lab of Prof. Markus Grütter in the Department of Biochemistry. We are focusing on the investigation of the structure/function relationship of proteins involved in apoptosis, innate immunity and trans-membrane signaling (PNAS (2008) 105:20251, Structure (2008) 16:1443, Structure (2007) 15:625, PLoS Biol (2007) 5:e7). We seek enthusiastic team players with experience in at least one of the following disciplines: protein X-ray crystallography, protein expression and purification, and eukaryotic expression systems. Experiences in membrane protein biochemistry will be an advantage. Good knowledge of English is mandatory. Candidates applying for the Post-Doc position should hold a PhD in a life science-related subject. All positions are time limited for three years. Salary will be according to the regulations of the Swiss National Science Foundation scheme. Please submit your electronic application including a CV, a list of publications (for the Post-Doc positions) and the names of two to three referees to Mrs. Salome Rittmeyer at the following address: secgruet...@bioc.uzh.ch Best regards, Peer Mittl