Hi all I am working with a multidomain protein whcih binds to a ligand. This protein exist in two different states, a) apo form of the protein is closed state and b) holo protein is an open state. One of the domain is mobile and have different conformation compared to its closed conformation. This domain have rotated by an angle of 15 degree and also translated with some Angstrom. Can any one explain me how to calculate the Translation distance as well as the rotation angle of the domain in the different states? I would appreciate the suggestions.
Thanks in advance Peter
