Postdoc Position in Protein Crystallography
A research position in protein crystallography at the postdoc level is available in the group of Clemens Steegborn in Bochum, Germany. Research in the laboratory is focused on understanding the molecular signaling mechanisms involved in aging processes and disease. In particular, we study mitochondrial signaling proteins and the cyclic nucleotide signaling network formed by nucleotdyl cyclases and their counterparts, phosphodiesterases. We use protein crystallography, combined with biochemical and enzymological methods and bioinformatics approaches, to obtain a molecular understanding of these interconnected signaling systems. We are looking for a Postdoc with experience in protein x-ray crystallography to join our team studying cyclic nucleotide signaling mechanisms (see, e.g., PNAS 105, 15720-5; J. Med. Chem. 51, 4456-64; NSMB 12, 32-7). Our laboratory is located at the Medical School of Ruhr-University Bochum. It offers access to state-of-the art equipment and facilities, and a stimulating environment for research in structural biology. The group strongly interacts with Eckhard Hofmann's group, sharing crystallography equipment and holding joint seminars, and is associated with the Max-Planck-Institute of Molecular Physiology in Dortmund giving us access to state-of the art x-ray facilities and synchrotron beamlines. Our lab offers excellent research opportunities and a stimulating environment for research in Structural Biology. The ideal candidate is a highly motivated Ph.D. with an interest in medically relevant questions. Experience in protein purification & crystallization and x-ray structure analysis is ABSOLUTELY MANDATORY. Additional experience in molecular biology would be an asset. Applications (including CV, research experience, and at least two names and contact information for references) should be sent, preferably per email as PDF attachment, to <mailto:[email protected]> [email protected] Evaluation of applications will start by June 9th. ---------------------------------------------------------------------------- ------- Jun.-Prof. Dr. Clemens Steegborn Ruhr-University Bochum Physiological Chemistry, MA 2/141 Universitaetsstr. 150 44801 Bochum, Germany phone: ++49 234 32 27041 fax: ++49 234 32 14193 email: [email protected]
