Hi, Sorry to sound stupid, could someone explain what does refmac do if one chooses "mixed (bref MIXED)" or "overall (bref OVER)" B factor refinement in the context of TLS refinement?
Is it something like: Isotropic for the main chain and/or waters and anisotropic for the side chain? Regards, Partha -- MRC National Institute for Medical Research Division of Molecular Structure The Ridgeway, NW7 1AA, UK Email: [email protected] Phone: + 44 208 816 2515
