Hi all,
I am trying to compare the binding affinities of two small proteins to a bigger receptor protein by interface analyis (computational interface alanine scanning by Rosettadock/Robetta server). I was wondering:
1. If it possible to use DDGs of the individual amino acid residues to predict binding affinities
2. If there is another method of predicting binding affinities in silico
Thanks,
Regards,
Josiah.
