I think it is up to the buyer to gain knowledge about prices from other 
companies. So I agree the survey on CCP4 was a good idea, but we should
stop the "legal" discussion here (or continue outside ccp4) - it's not
really crystallography :-)

Clemens

> -----Ursprüngliche Nachricht-----
> Von: CCP4 bulletin board [mailto:[email protected]] Im Auftrag von
> Jacob Keller
> Gesendet: Wednesday, July 15, 2009 7:05 PM
> An: [email protected]
> Betreff: Re: [ccp4bb] Summary IPTG suppliers (mainly Europe)
> 
> I think that since there is not a uniform price, competition is not
> playing
> a significant enough role in pricing. So I ask: why is competition not
> playing a role? And I would suggest: perhaps the bigger companies are
> exploiting the lack of knowledge about the true market price of IPTG.
> Happily, it seems that CCP4bb is ruining this dubiously-ethical edge.
> 
> I am not sure about European law: is it theoretically illegal to charge
> 10x
> market value without the buyer's knowledge? In Jewish monetary law,
> this is
> forbidden, and since there are similarities between the legal systems,
> I
> would guess that there might be a problem here.
> 
> Jacob Keller
> 
> *******************************************
> Jacob Pearson Keller
> Northwestern University
> Medical Scientist Training Program
> Dallos Laboratory
> F. Searle 1-240
> 2240 Campus Drive
> Evanston IL 60208
> lab: 847.491.2438
> cel: 773.608.9185
> email: [email protected]
> *******************************************
> 
> ----- Original Message -----
> From: "Clemens Steegborn" <[email protected]>
> To: "'Jacob Keller'" <[email protected]>;
> <[email protected]>
> Sent: Wednesday, July 15, 2009 7:01 AM
> Subject: AW: [ccp4bb] Summary IPTG suppliers (mainly Europe)
> 
> 
> 
> Hi Jacob,
> 
> I am not sure I understand why a spread in pricing indicates illegal
> activity.
> Wouldn't uniformly high prices indicate something illegal, and very
> different
> prices just indicate you have a choice of suppliers, qualities etc?!?
> 
> And just to mention two more supplier names (again: different brands,
> different
> prices) for IPTG we never had problems with:
> 
> Applichem, current promotion price 155 Euro for 25 g
> 
> Roche, promotion starting Aug (according to a Roche sales person) 128
> Euro
> for 5 g
> 
> Best
> Clemens
> 
> 
> > -----Ursprüngliche Nachricht-----
> > Von: CCP4 bulletin board [mailto:[email protected]] Im Auftrag
> von
> > Jacob Keller
> > Gesendet: Tuesday, July 14, 2009 7:45 PM
> > An: [email protected]
> > Betreff: Re: [ccp4bb] Summary IPTG suppliers (mainly Europe)
> >
> > When there is a greater-than-10-fold range of prices, as here, it
> seems
> > that
> > there is unfair business going on. I am no expert on European
> business
> > law,
> > but I suspect there might be something illegal here.
> >
> > Jacob Keller
> >
> > *******************************************
> > Jacob Pearson Keller
> > Northwestern University
> > Medical Scientist Training Program
> > Dallos Laboratory
> > F. Searle 1-240
> > 2240 Campus Drive
> > Evanston IL 60208
> > lab: 847.491.2438
> > cel: 773.608.9185
> > email: [email protected]
> > *******************************************
> >
> > ----- Original Message -----
> > From: "Mark J. van Raaij" <[email protected]>
> > To: <[email protected]>
> > Sent: Tuesday, July 14, 2009 11:56 AM
> > Subject: [ccp4bb] Summary IPTG suppliers (mainly Europe)
> >
> >
> > Current EU IPTG prices in euros, approximate, without tax, delivery
> or
> > currency exchange fees. Prices are quoted as to my best knowledge,
> but
> > of course may be different when you order at a different time or from
> > a different place. I do not claim it is complete.
> >
> > Apollo Scientific (UK): 5 g 18 euros, 25 g 85 euros
> > Biosynth (Switzerland): 10 g 40 euros, 25 g 89 euros, 50 g 160 euros,
> > 100 g 286 euros
> > ForMedium (UK): 1 g 9 euros, 5 g 28 euros, 10 g 51 euros, 25 g 118
> > euros, 100 g 378 euros, 250 g 765 euros
> > Melford (UK): 1 g 10 euros, 5 g 31 euros, 10 g 56 euros,  25 g 131
> > euros, 50 g 244 euros, 100 g 450 euros
> > Nzytech (Portugal): 1 g 28 euros, 5 g 52 euros
> > Eurogentec (via Cultek): 1 g 21 euros, 5 g 84 euros
> > Qiagen (via Izasa): 5 g 142 euros
> > Promega: 50 g 1140 euros, 5 g 181 euros, 1 g 61 euros
> > Invitrogen: 1 g, 44 euros
> > Sigma-Aldrich: 5 g 250 euros, 10 g 494 euros
> >
> > Fermentas was also mentioned at 33 pounds for 5 g, but their web does
> > not let you see the price unless you register (it also does not
> > mention Spain in the shipping list, perhaps it has a distributor here
> > I am unaware of).
> > It appears UK/Swiss companies are the cheapest, and the UK is in
> > Europe, although some people seem to think otherwise. Seriously, for
> > us ordering the UK is as easy as ordering from Spain or other
> European
> > countries. I am not sure how easy ordering from Switzerland would be,
> > I have never tried...
> > All people give good refs of the supplier used (i.e. absence of
> > expression problems), except for one person, who only uses Sigma IPTG
> > after problems with other sources.
> >
> > Another supplier mentioned without EU distributors was:
> > Gold BioTechnologies: 25 g 99 USD, 100 g 309 USD, 300g 799 USD
> >
> > Several people mentioned Studiers auto-induction methods, which
> avoids
> > having to use IPTG and gives them better cell density and, in some
> > cases, more expression of soluble protein.
> >
> > Thanks to all for their comments and knowledge of companies I had
> > never heard of and did not find with Google,
> >
> > Mark
> >
> >
> >
> >
> > Mark J. van Raaij
> > Dpto de Bioquímica, Facultad de Farmacia
> > Universidad de Santiago
> > 15782 Santiago de Compostela
> > Spain
> > http://web.usc.es/~vanraaij/

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