Dear all,
I have a 1.6A data in P21 spacegroup whith good quality, wich is
assumed to contain 4 Set-Met. But the patterson map
appears strange. There is a very big heavy peak in the harker section, and
seems like an irregular ellipse, while there are small
peaks very near(almost connect) to this big peak and the origin, say about
0.05 in fraction, looks like cross peaks.It looks like the
heavy atoms are very close if there are more than one. I tried several
programs and many heavy atom coordinates sits, but none
of them can solve it. Shelxd got a set of sites looks best with set the
minimum distance to 1A, since the patterson map from it
looks like the experimental patterson map, though not very much. But with
this HA sites can get nothing meaningful. By the way,
it is a small molecule with no more than 150 residues, one molecule/ASU.
According to shelxc the signal is not strong, can only
be used to aroud 2.2A.
Any suggestions would be
appreciated!
