Hello All- I figured I would post this here since there are some protein biochemists who frequent the site, and many of the crystallographers may know of protein biochemists who might be looking for a job. Please pass this along to any potentially interested parties.
Thanks! Steve P.S. Please do not respond to me directly if interested in the position, our HR group requires that you apply through the online tool. --------------------------------------- Stephen M. Soisson, Ph.D. Global Structural Biology Merck Research Laboratories Phone: (215) 652-6185 Merck & Co. Inc., established in 1891, is a global research-driven pharmaceutical company dedicated to putting patients first. Join us and experience our culture first-hand - one of strong ethics & integrity, diversified experiences and a resounding passion for improving human health. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. This exciting position within Merck Global Structural Biology at the West Point, PA site will enable drug lead discovery and optimization through the production and characterization of proteins for use in X-ray crystallography and screening. The incumbent will perform protein purification and characterization of recombinant proteins from prokaryotic and eukaryotic hosts. Duties will include exploring new technologies to optimize purification methods, and communicating results at departmental meetings. Education Requirement: BS in Biochemistry or related discipline with 4+ years experience MS in Biochemistry or related discipline with 3+ years experience Required: Demonstrated success in high-quality purification of recombinant proteins (milligram scale) from both eukaryotic and prokaryotic hosts, using state-of-the-art technologies (e.g. AKTA FPLC/Purifier/Express) is essential. Experience working with both untagged and affinity-tagged (e.g. His, GST, FLAG, HA etc) recombinant proteins is required. Experience with protein characterization (e.g. SDS-PAGE, Western analysis) and protein concentration determination via standard spectroscopic methods (Bradford, A280nm etc). Demonstrated ability to scientifically plan and execute multiple purification projects simultaneously, to ensure the team goals are met. Excellent communication skills (written, presentation, and oral). Ability to work in a team-oriented environment within timelines. Desired: Experience in the application of biophysical characterization methods (e.g. Biacore, Thermofluor, mass spectrometry, protein NMR) and activity analysis (e.g. enzyme kinetics) is a strong plus. Knowledge of molecular biology, structural biology or HTS is a plus. Familiarity with protein crystallization is a plus. Industry experience is a plus. Consistently cited as a great place to work, we discover, develop, manufacture and market a wide range of vaccines and medicines to address unmet medical needs. Each of our employees is joined by an extraordinary sense of purpose - bringing Merck's finest achievements to people around the world. We offer an excellent salary and an industry-ranked benefits program, including tuition reimbursement, work-life balance initiatives and developmental programs at all levels. Merck's retirement package includes a pension plan and one of the best 401(k) plans in the nation. To be considered for this position, please visit our career site at www.merck.com/careers to create a profile and submit your resume for requisition # BIO002197. Merck is an equal opportunity employer, M/F/D/V - proudly embracing diversity in all of its manifestations. Our work is someone's hope. Join us. Where patients come first - Merck Notice: This e-mail message, together with any attachments, contains information of Merck & Co., Inc. (One Merck Drive, Whitehouse Station, New Jersey, USA 08889), and/or its affiliates (which may be known outside the United States as Merck Frosst, Merck Sharp & Dohme or MSD and in Japan, as Banyu - direct contact information for affiliates is available at http://www.merck.com/contact/contacts.html) that may be confidential, proprietary copyrighted and/or legally privileged. It is intended solely for the use of the individual or entity named on this message. If you are not the intended recipient, and have received this message in error, please notify us immediately by reply e-mail and then delete it from your system.
