Dear Colleagues:

We are delighted to announce that the 5th International Conference on 
Structural Analysis of Supramolecular Assemblies by Hybrid Methods will be held 
from March 10-14, 2010 in Lake Tahoe, California at the Granlibakken Conference 
Center. We invite you to visit our Symposium website at:, register for the Symposium, submit 
an abstract, encourage all other interested parties to attend, and display the 
enclosed meeting poster.

This Symposium builds on a series of very successful previous meetings on the 
same theme from 2004-2008. As in previous years, the overall goal is to 
illustrate the power of combining state of the art methods to tackle important 
and challenging biological problems and to identify limitations and gaps in 
currently practiced hybrid methods. The central premise is that gaining a 
comprehensive understanding of the highly sophisticated machines, complexes, 
and organelles of the cell requires the coordinated application of a number of 
complementary biophysical approaches (hybrid methods). New innovations at the 
2010 meeting will include a special workshop on "Harnessing Different 
Wavelengths of Electromagnetic Radiation", which will feature the rapidly 
developing fields of subdiffraction light microscopy and other emerging imaging 
techniques (e.g., X-ray tomography), as well as new advances within more 
"traditional" hybrid approaches such as the interfaces between electron 
microscopy, X-ray crystallography, and computational biology.  Featured topics 
will also include other biophysical methods, proteomics and cell biology.

The meeting will be divided into seven Scientific Sessions
and one Special Methods Workshop

Session I: Hybrid Approaches to Macromolecular Filaments
Session II: Hybrid Approaches to Membrane Complexes
Session III: Hybrid Approaches to Dynamic Assemblies
Session IV: Computational Approaches to Hybrid Analyses
Session V: Hybrid Approaches to Global Analyses
Session VI: Hybrid Approaches to Cell Biology
Session VII: Hybrid Approaches to Nanomachines
Special Methods Workshop: Harnessing Different Wavelengths of Electromagnetic 

We are fortunate to have recruited two outstanding Keynote Speakers: Stephen C. 
Harrison (Harvard) and Thomas D. Pollard (Yale), as well as a great program of 
platform speakers who utilize multiple approaches to investigate a variety of 
complex biological systems. Additional platform speakers and all of the 
speakers for the Special Methods Workshop will be selected from submitted 

Sincerely yours,

The Organizing Committee: Wes Sundquist, Chair, Phoebe Stewart, Co-Chair, Dorit 
Hanein, Nobutaka Hirokawa, Felix Rey, Alasdair Steven, and Bill Weis.
Rachel Bookman, Conference Secretariat.

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