Dear all,
I have refined a structure where several sidechains have only partial
2Fo-Fc density ( 1 X sigma). I see strong Fo-Fc density in both omit maps and
when I delete the sidechains, suggesting the presence of the sidechain.
However, the density is never complete and sometimes only covers the C-beta
atoms. The structure is at 2.9A and the Rfree is approximately 25% using
BUSTER-TNT (29% with Refmac). I am not sure how to interpret this and was
wondering if it suggested a disordered or dynamic structure. Are there any
reports of such structures in the literature?
Thank you
Kumar
