Applicants are invited for a post doctoral position at the Carlsberg
Laboratory to study structure and activity of starch branching and
debranching enzymes during barley grain filling and germination.
The amount and quality of starch in barley are controlled by the enzymes
involved in its biosynthesis; among them the branching (BE) and
debranching enzymes (DBE). DBEs play an additional role during
mashing/malting, since the fermentability of starch relies on this
activity to degrade the α-1,6 branches of amylopectin. The aim of the
present project is to characterize differences in BE and DBE activities
in barley landraces during grain filling and germination and to seek to
correlate these differences with exogenous proteins and with
structural-functional properties of specific BE and DBE. Methods
employed will include protein-protein interaction proteomics,
enzymology, X-ray diffraction analysis of starch and protein. Our
laboratory is fully equipped for all aspects of molecular biology,
protein chemistry, protein crystallography and biophysical
characterization of proteins.
Applicants must have experience with proteomics, enzymology and/or
biophysical characterization of proteins. Experience with production and
purification of recombinant proteins will be considered an advantage.
The position is a three-year position with one-year contract
re-negotiation. Inquiries should be directed to: Anette Henriksen,
E-mail: [email protected]. To apply, please send a CV including a brief
description of research interests and accomplishments, and the names and
addresses of two referees to: Anette Henriksen, Protein Chemistry Group,
Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Copenhagen,
Denmark E-mail: [email protected]
The Protein Chemistry Group at Carlsberg Laboratory studies starch
metabolism from a structural-biochemical perspective. The Laboratory was
set up in Copenhagen 1875 by the founder of Carlsberg to develop a
scientific basis for malting, brewing, and fermenting operations, and
it has a long record in protein chemistry, yeast biology and plant
physiology.
--
Anette Henriksen, Prof., Ph.D.
Carlsberg Laboratory, Biostructure Group,
Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.
Phone: +45 33275222. Fax: +45 33274765
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