Hi Azadeh, I looked into this and other related methods extensively once, and came out with the understanding that SCA is not really the best of this type of analysis (you can read some of the papers out there which analyze the several methods). I found that the java package from Mark Gerstein's group at Yale does any/all of the analyses in parallel (if you want) and is relatively easy to set up. The best, as I recall, was the one based on:
Gobel,U. et al. (1994) Correlated mutations and residue contacts in proteins. Proteins: Struct. Funct.Genet., 18, 309-317. I think you need an MTA for the actual SCA software, as well. Jacob ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program Dallos Laboratory F. Searle 1-240 2240 Campus Drive Evanston IL 60208 lab: 847.491.2438 cel: 773.608.9185 email: [email protected] ******************************************* ----- Original Message ----- From: Azadeh Shahsavar To: [email protected] Sent: Monday, January 18, 2010 4:25 AM Subject: [ccp4bb] SCA Dear all, Does anyone have the current (or old) version of SCA? (SCA: statistical coupling analysis) It should be as a toolbox of Matlab software. Thank you in advance, Azadeh
