Dear Crystallographers,
Is anybody aware of a calculator for vapor diffusion experiments to plot
concentrations of various solvent components as a function of time? For a
simple example, what happens when I mix a protein solution containing 50mM
NaCl 1:1 with a reservoir containing 50% MPD but no salt? Where is the vapor
diffusion equilibrium, and how does the drop composition change as a
function of time? More complicated would be experiments involving volatile
components other than water, as I think, for example, ethanol would almost
instantly equilibrate, then the water diffusion would kick in over a longer
time scale. Even more complicated would be pH-dependent volatilities such as
acetate. I don't think this would be impossible to figure out, but it would
be nice if there were a pre-existing tool/server to do such.
Regards,
Jacob Keller
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Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.491.2438
cel: 773.608.9185
email: [email protected]
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