PISA can give you such estimate, you may try standalone pisa in CCP4 or on-line (google on "EBI PISA")
Eugene On Thu, Apr 1, 2010 at 8:36 AM, Mike England <[email protected]> wrote: > Hi All, > > I would greatly appreciate your comments on following: > > I would like to know the quantitative relation between "Solvent > excluded area" (calculated by Areaimol at CCP4i) and "free energy of > binding" or "binding affinity" of the DNA-protein or protein-protein > interactions. > Is there some free software available to do so? > > Thank you very much. > > Mike >
