Hi -
You should not use literature as proof; every protein is different.
You would need to do site directed mutagenesis experiments,
to show which binding mode is relevant.
I am also not sure what 'completely different' means, if the ligands
are in different sites,
it could also be of interest, eg an allosteric effect.
A.
On 17 May 2010, at 4:20, <Rain Field> <[email protected]> wrote:
Thank you for your valuable advice.
My situation is this:
I got two completely different structures by soaking and co-
crystallization.
I believe co-crystallization. But I don't know if I can find the
literature which I would cite as a proof.
Rain Field
