There is an immediate opening for a postdoctoral position in the Goldman group in the Institute of Biotechnology at the University of Helsinki (http://www.biocenter.helsinki.fi/bi/xray/goldman/Home_.html). My group focusses on proteins in or near the cell membrane. In particular, we have a series of projects aimed at understanding the structure and function of bacterial trimeric autotransporter adhesins (TAAs) (eg: Nummelin et al., EMBO J, 23, 701-771, 2004; Leo et al., Infect Immun, 78, 3226-3236, 2010; Leo et al., Mol. Immunol., 46, 2860-6, 2009). Our current goals are to solve the structure of TAA-ligand complexes, and to understand the mechanism of TAA folding.
The Goldman group is well-equipped, with several GE Healthcare Akta systems for protein purification, a robotic crystallisation and visualisation unit (Cartesian, Oryx, Mosquito LCP coming), as well as standard x-ray crystallography and molecular biology equipment. I head the Finnish crystallography BAG at the ESRF, and we have access to the ESRF on a monthly basis. The successful candidate will have a strong background either in protein structural work or in protein production and characterisation, with a desire to learn the other field. Experience in automation will be a great plus, as the candidate will also have responsibility for the management of the robot crystallisation facility, in conjunction with the programmer and technicians who run it. The Institute of Biotechnology at UH provides a richly collaborative environment for studying problems at the interfaces between cell, molecular, developmental and structural biology. For further information, please contact Professor Adrian Goldman, Institute of Biotechnology, University of Helsinki. Email: [email protected] or phone: +358 (0)9 191 58923. Applications: please send a complete c.v., publication list and the names and addresses of two referees to me by email. The University of Helsinki is an equal opportunity employer and salary will be on the standard University payscale, depending on experience.
