On Wednesday 25 August 2010 03:13:53 pm Hailiang Zhang wrote:
> Hi Garib:
>
> Actually I tried coot real space refine zone, but the model seems not
> sliding into the best density map (I also tried dragging it around, but
> still not working fine). Then I found some comments saying minimizing the
> difference between 2mFo-DFc and Fc may be better, thats why I am asking
> for this.
Wait a minute. If you are minimizing a residual based on differences
between Fo and Fc (never mind the precise coefficients), how is this
"real space refinement"?
(puzzled) Ethan
>
> Best Regards, Hailiang
>
> > Why you do not use coot? It does exactly what you want.
> >
> > regards
> > Garib
> >
> > On 25 Aug 2010, at 22:33, Hailiang Zhang wrote:
> >
> >> Hi,
> >>
> >> Can some utilities of CCP4 do the real-space refinement locally
> >> with the
> >> residue range explicitly specified?
> >>
> >> By the way, I have registered phenix bb. Just didn't realize this
> >> before,
> >> sorry again.
> >>
> >> Best Regards, Hailiang
> >
> >
>
--
Ethan A Merritt
Biomolecular Structure Center, K-428 Health Sciences Bldg
University of Washington, Seattle 98195-7742
