Actually I cut a small domain from the well-defined structure (just for a
test). The missing part showed in 2mFo-DFc map but not in both mFo and Fo
maps, and the mFo and Fo maps are so close so that I wonder whether figure
of merit generated by SIGMAA helps or not in this situation...

Best Regards, Hailiang

> On Tue, 2010-08-31 at 13:15 -0400, Hailiang Zhang wrote:
>> Is the difference
>> between mFo and Fo maps supposed to be very small?
>
> For an essentially correct model, yes. The major advantage of (2mFo-DFc)
> maps is suppression of model bias, so if you don't see much difference
> then your model is very well refined.  For illustration, introduce a
> systematic error on purpose and see which map gives you better result.
>
> --
> "I'd jump in myself, if I weren't so good at whistling."
>                                Julian, King of Lemurs
>
>

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