>Dear All, > >I am trying to find out which molecules are frequently used by X-ray >crystallographers serving as cryoprotectants or as buffer molecules. The >idea behind this is to sort native ligands from molecules that appeared in >the electron density just because they were used in the crystallization >buffer or as a cryoprotectant. Can anybody point out literature, a web site, >or simply provide a (subjective) list extending my collection of GOL, EDO, >and different size PEGs? What about sugars? > >Thanks for your help, > >Chris
We have listed and categorized many of the chemicals that you are looking for: http://store.p212121.com/categories/Chemicals/ Disclosure: I am associated with this commercial website. Items that are not listed, but would be worth considering: MES Polyethylene Glycol Monomethylether (350, 550, 750, 2000, 5000) PEG 1,500 PEG 6,000 PEG 10,000 PEG 20,000 Paratone-N 1,4-Dioxane 1,6-Hexanediol (+/-)-2-Methyl-2,4-pentanediol Jeffamine® ED-2001 Ethylene imine polymer Jeffamine® M-600® Reagent Pentaerythritol ethoxylate (15/4 EO/OH) Pentaerythritol propoxylate (5/4 PO/OH) Pentaerythritol ethoxylate (3/4 EO/OH) Pentaerythritol propoxylate (17/8 PO/OH) Perfluoropolyether PFO-X175/08 Poly(acrylic acid sodium salt) 5,100 Polypropylene glycol P 425 Polyvinylpyrrolidone K 15 In addition to the chemicals already mentioned it may be worth including detergents and enzymatic substrates. I hope that helps. Take Care, Sean
