The oxygen appears to approach sulfur on the back of the bisector of the C-S-C angle but this is not as accurate as a small molecule structure.
There is a paper Rosenfield and Parthasarathy in JACS ~1975 - 1980 that studies how electrophiles and nucleophiles approach sulfur. That paper should answer your question. The short distance has error but I think in the equatorial plane the approach is closer. Now it would be interesting to review protein structures to see how electrophiles and nucleophiles approach sulfur. Jackie Vitali 2010/9/23 Joe Yap <[email protected]> > Dear all, > > My apologies for this non-ccp4 question. > > I have a structure that shows the oxygen atom of a ribose facing the S of > the S-adenosyl-homocysteine (SAH). > > My question is can the O and S make any kind of non-bonded interaction? The > distance between the O and S atoms is about 2.16A. I have attached a > picture of this. > > I tried to search the literature but could not find any satisfying solution > to my query. > > Please enlighten. > > Thank you. > > Best regards, > > Joe Yap > > > >
