Hi Tri,

To me, the first 3 pictures suggest that there is a faint greenish tinge in the 
little shapes (hopefully crystalline) there. I guess the idea of the Topaz chip 
is that you can take it as is to the x-ray beam or am I wrong?  

   Cheers,

              Boaz

----- Original Message -----
From: Tri Ngo <[email protected]>
Date: Wednesday, September 29, 2010 10:50
Subject: [ccp4bb] The color of GFP crystals?
To: [email protected]

> Dear CCP4 community,
> 
> I wonder if anybody has experience about the color of GFP 
> crystals. Is there
> any chance that the GFP crystal will become colorless? We are 
> working on one
> membrane protein fused with GFP. Since we got some crystals 
> which didn't
> show any color (Condition 01), I am not sure if I should go for
> optimization.
> 
> Please check the link below for the image details:
> http://www.docstoc.com/docs/55950590/GFP-crystals
> 
> Because of the limited amount of sample, we used Topaz system 
> (screeningchip) to do the screening and there is no way to 
> confirm these crystals are
> actually protein crystals. I noticed that the crystals are 
> bigger day by
> day. Is it a good sign to confirm the protein crystals?
> 
> Thank you very much for your helpful information!
> 
> Best wishes,
> 
> *
> TriNgo
> 
> *
> 
> Structural Biology Lab
> 
> School of Medicine - Sungkyunkwan University
> 
> Phone: 031-299-6150
>

Boaz Shaanan, Ph.D.
Dept. of Life Sciences
Ben-Gurion University of the Negev
Beer-Sheva 84105
Israel
Phone: 972-8-647-2220 ; Fax: 646-1710
Skype: boaz.shaanan‎

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