We are seeking outstanding postdoctoral candidates to investigate the structure-function relationships in membrane proteins. The structural studies in the laboratory include several broad categories of membrane proteins, with a focus on the determination of structures of membrane proteins in complex with soluble binding partners. Prior experience in protein expression and purification would aid in pursuing these projects, as would experience in x-ray crystallography.
The Center for Structural Biology at the Vanderbilt University Medical Center has excellent resources for pursuing structural studies. The on-campus x-ray facilities include a high-brilliance Bruker micro star x-ray generator with a CCD detector, and an xcalibur system. A state-of-the art robotic crystallization facility includes a Mosquito nano-liter pipetting robot, a Hamilton Star-let liquid handler, a cubic lipid phase pipetting robot, and a Formulatrix imager. Vanderbilt University has purchased a share in a beamline at the Advanced Photon Source to allow for guaranteed synchrotron access, which provides us with an average of 24 hours on 3 beamlines concurrently every 3 weeks. Vanderbilt University is located in Nashville, an exciting multi-cultural center that houses the music industry in this region. The mild climate makes a pleasant background for this diverse and lively city. Qualified applicants should send a cover letter and cv by email to [email protected]. ----------------------------------------- T. M. Iverson, Ph.D. Department of Pharmacology 460 Robinson Research Building 23rd Avenue South @ Pierce Vanderbilt University Medical Center Nashville, TN 37232-6600 Office: (615) 322-7817 Fax: (615) 343-6532 Email: [email protected] Lab URL: http://www.mc.vanderbilt.edu/root/vumc.php?site=iversonlab Department URL: http://www.vanderbilt.edu/pharmacology
