[ccp4bb] Differences between refmac_5.5 and refmac_5.2

[Hailiang Zhang]

Hi,

I found there are many changes between refmac_5.5 and refmac_5.2. For
example, the key word "REFI BREF OVER" will result in totally different
results under these 2 versions. Based on my input PDB with anisotropic B
pre-refined, refmac_5.5 gave a much higher R/Rfree than refmac_5.2. Can
somebody explain the difference and give me some suggestions on how to
modfiy the keyword in refmac_5.5 to match what refmac_5.2 have done by
using "REFI BREF OVER"?

Thanks!