Try pointless first with your P222 data and as output option it will provide 
you the most likely space group. The warning in the GUI is just a warning, 
maybe P21 21 21 is not the right space group that's why you get the warning :-)

In terms of reprocessing your data, you are not dependent on HKL2000, take 
Mosflm or XDS no license required, hassle free reprocessing of your data.

Jürgen

-
Jürgen Bosch
Johns Hopkins Bloomberg School of Public Health
Department of Biochemistry & Molecular Biology
Johns Hopkins Malaria Research Institute
615 North Wolfe Street, W8708
Baltimore, MD 21205
Phone: +1-410-614-4742
Lab:      +1-410-614-4894
Fax:      +1-410-955-3655
http://web.mac.com/bosch_lab/

On Oct 17, 2010, at 3:34 PM, Daniel Bonsor wrote:

> Hi all,
> 
> This maybe a simple/stupid question. I collected data at the synchrotron, 
> integrated and scaled the data in P222 using HKL2000, though I should of 
> scaled the data as P212121. 
> 
> When I try to reindex using Reindex I get a message of
> 
> !!!! You are changing the symmetry of merged data  are you SURE you know what 
> you are doing!!!!
> WARNING: ** Symmetry change of merged data **
> 
> I am unsure of what I am doing in this case. Currently I cannot reprocess the 
> data as I do not have a working version of HKL2000. So my question is can I 
> reindex scaled data and what I should be doing with the GUI of reindex?
> 
> Thanks in advance for advice.
> 
> Just in case it is important my cell dimensions are 109.9280  160.3030  
> 186.2200   90.0000   90.0000   90.0000 and the resolution is 2.7 Angstrom.

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