Hi, I have seen this happening when I had NCS and did not include it in refinement. Rwork drops and Rfree increases. In this case the difference became small when I included the NCS.
Also if your Rmerge is high and you include all reflections in refinement, Rfree is high. In my experience, by excluding F < sigma reflections you drop Rfree a lot. My limited experience suggests errors in the data and/.or in the way you handle the data. Jackie Vitali On Mon, Oct 25, 2010 at 5:10 PM, Rakesh Joshi <[email protected]> wrote: > Hi all, > > Can anyone comment, in general, on diverging Rcryst and Rfree > values(say>7%) for > structures with kind of low resolutions(2.5-2.9 angstroms)? > > Thanks > RJ >
