Postdoctoral Research Fellow Structural Biology of DNA Repair Complexes - Ref: 120
CR-UK DNA Repair Enzymes Group Genome Damage and Stability Centre School of Life Sciences UNIVERSITY OF SUSSEX A Cancer Research UK-funded Postdoctoral position is available immediately in the laboratory of Professor Laurence Pearl FRS to study the structural basis for assembly and specificity of multi-protein complexes involved in the recognition and repair of DNA breaks. The internationally renowned Genome Damage and Stability Centre and the School of Life Sciences is very well equipped for all aspects of modern structural biology, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic systems, biochemistry, biophysics and X-ray crystallography. Excellent synchrotron access (~ 2 days/month) is available through rolling beam-allocation programmes at Diamond and ESRF. Applicants must have a PhD, and experience in recombinant expression and protein purification. Experience of crystallization and X-ray crystallography would be an advantage. Information on our previous work in this field can be found by searching PubMed (pearl lh [au]). The postholder will be responsible for expression, purification, crystallization and structure determination of protein-protein and protein-DNA complexes, and downstream biochemical characterisation. Fixed term to end Sept 2012 in the first instance - Full Time Salary: £29,853 - £35,646 per annum Informal enquiries can be made to Professor Pearl [email protected]. Closing date: 7 January 2011 For full details and how to apply see www.sussex.ac.uk/jobs The University of Sussex is committed to equality of opportunity -------------------------------------------------------------------------------- Laurence H. Pearl PhD FMedSci FRS Professor of Structural Biology and Head of School of Life Sciences University of Sussex, Brighton, BN1 9RH, UK Phone +44-(0)1273 876 544: PA +44-(0)1273 872 699 -------------------------------------------------------------------------------- "Live Modestly and do Serious Things .. " - Dorothy Crowfoot Hodgkin --------------------------------------------------------------------------------
