A postdoctoral position at Cold Spring Harbor Laboratory (CSHL) is available to study molecular mechanisms of ion/substrate transport and enzymatic processes at the biological membrane by structural, electrophysiological, and biochemical approaches. Our goal is to understand molecular basis for neurological disorders and diseases caused by disruption of cellular calcium homeostasis and apply the gained information for development of therapeutic compounds.
We are equipped with a state-of-the-art facility to conduct cutting-edge membrane/glyco protein crystallography including a high-throughput protein screening system, an automated crystallization screening device, and a recently updated home x-ray source. We are also equipped with electrophysiology rigs, an isothermal titration calorimetry device, and a fluorometer to conduct functional studies. CSHL is located in the suburb of New York City and is within 45 min driving distance from the National Synchrotron Light Source at Brookhaven National Laboratory. A highly collaborative environment and meetings and courses at CSHL provide a unique opportunity to interact with scientists from various fields within and outside of CSHL. Candidates must hold (or soon expect to hold) PhD in biochemistry, molecular biology, biophysics or related fields. Strong background in molecular biology, biochemistry, and large-scale protein expression in eukaryotic/prokaryotic cell-lines is required. Experience in x-ray crystallography or other techniques in structural biology, is desirable but not necessary. Applicants with experiences in electrophysiology, and neuroscience-related biochemistry are also welcomed. For more information, please check the laboratory website (http://www.cshl.edu/Faculty/furukawa-hiro.html) and contact via email. Please send CV, a brief summary of research experience and interest, and three references to Hiro Furukawa by email at furuk...@cshl.edu
