Subject: Postdoctoral Fellowship at Scripps Florida in Crystallography Postdoctoral Research Associate positions are immediately available for structure-function studies of cytoskeletal proteins that control signaling downstream of adherens junctions and focal adhesions. Fellows will join an exciting research environment of the Izard laboratory in new state-of-the-art facilities of the Scripps Florida campus of The Scripps Research Institute (TSRI), which is renowned in the Structural Biology field. The Izard laboratory has made many contributions in the cytoskeleton field (http://www.scripps.edu/florida/cancerbio/izard).
The position provides an outstanding training program in protein biochemistry and structure, and also in molecular and cellular biology, in a highly dynamic and team-oriented research program. Successful candidates will work in a cutting-edge research environment that tackles this important new arena in cancer and cell biology. The laboratory has outstanding facilities for cell biology, molecular biology, protein expression, purification, and biochemistry, and protein crystallography. Scripps Florida provides an incredibly rich scientific environment. Notably, TSRI faculty include an outstanding cadre of senior colleagues, including three Nobel Laureates and about twenty Members of The National Academy of Sciences, including several in crystallography and biophysics. In 2008, Scripps Florida moved into three new, state-of-the-art research buildings and will expand to eventually house 80 faculty-level investigators. Scripps Florida has a large cast of outstanding Cores that facilitate basic research and drug development. The unique infrastructure at Scripps Florida includes the application of unique chemical, genomic, proteomic, informatics, and high-throughput screening and engineering tools for the discovery of novel biomolecules. Scripps Florida is a new member of the South East Regional Collaborative Access Team (SER-CAT) that constructed two beam lines at the Advanced Photon Source (APS) at Argonne National Laboratory. The insertion device and bending magnet beam lines are available for all the synchrotron-related data collection needs for the post-doctoral fellows. Scripps Florida provides a HighFlux X-ray diffraction system, specifically a Rigaku MicroMax-007 HF, a second-generation true microfocus rotating anode generator. Scripps Florida also provides an Osmic VariMax optics system and the Proteros Free Mounting System to control the humidity and to optimize diffraction characteristics, including resolution, mosaicity, and anisotropy, as well as reduced X-ray background. Finally, the X-ray laboratory houses the mar345 Image Plate detector. Palm Beach County is one of the most sought-after communities in the country and offers residents an incomparable lifestyle in a family-friendly community with public playgrounds and parks and access to world-class shopping and unmatched outdoor recreation. It is one of the safest communities in the United States with virtually no crime. The Atlantic Ocean with its 45 miles of spectacular beaches and signature Coconut Palms provides an exclusive getaway in a warm, sunny climate throughout most of the year. There are a number of exquisite art galleries as well as arts and crafts festivals. This golfer's paradise is also home of the Professional Golfers Association of America (PGA). Applicants must have a Ph.D. degree and experience in protein crystallography. Please send CV, a summary of research experience and interests, and names, addresses, e-mail and telephone numbers of 3 references to: Dr. T. Izard ([email protected]) Associate Professor with Tenure Director, Macromolecular Crystallography Scripps-Florida Cell Adhesion Laboratory Department of Cancer Biology The Scripps Research Institute Jupiter, FL 33458
