Dear experts,

Sorry for a  simple question but confusing me so much!

Does it make bad effects on determining the number of identical molecules in
ASU by choosing low symmetry space group.
For example,If I choose lowest symmetry(p4) instead of  higher one(p43212).
Does it cause any trouble in determining structure while we try to find the
solution by molrep.
If molrep compare the patterson of observe and model in P1 space group, it
doesn't matter in choosing a lower s.g.?

Any suggestion will be appreciated. Thanks in advance.

Ting wei

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