A Ph.D. position is available to study the structure and function of macromolecular complexes governing the mitotic spindle orientation in asymmetrically dividing cells. To understand how these proteins functions and are coordinated with the cellular polarity, we follow a multidisciplinary approach combining structural and cell biology. These studies are expected to have a major impact on our understanding of stem cell biology, with possible applications at the forefront of anticancer therapy and regenerative medicine.

We seek a motivated and enthusiastic student, who has recently obtained a university degree in Life Science disciplines. Some experience in biochemistry or structural biology would be advantageous, though not required. Willingness to study protein functions with biochemical and biophysical methods, as well as interest in learning protein crystallography are essential. The Ph.D. position is within the SEMM "Ph.D. in Molecular Medicine" program (http://www.semm.it/).

The Structural Biology Department of the IFOM-IEO Campus is equipped with the state-of-the-art apparatus for protein purification, characterization and crystallization, and has good access to the synchrotron beamlines. Successful candidates will benefit from a stimulating and collaborative environment within the Campus (http://www.ifom-ieo-campus.it/ ).

Applicants should send their enquiries by e-mail to Marina Mapelli ([email protected] ). They should also ask two referees to send letters of recommendation at the same electronic address.


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Marina Mapelli, PhD
Department of Experimental Oncology
European Institute of Oncology
Via Adamello 16, I-20139 Milan, Italy
tel:  ++39-02-94375018
email: [email protected]
web: http://www.ifom-ieo-campus.it/research/mapelli.php

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