It's not a protein, but here's another example: the PreQ1 Riboswitch. In this case the two methods revealed different structures, but the NMR group was able to determine that the differences were due to calcium in the crystallization condition.
Crystal Structure: Nat Struct Mol Biol. 2009 Mar;16(3):343-4. Epub 2009 Feb 22. Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase. Klein DJ, Edwards TE, Ferré-D'Amaré AR. NMR Structure: Mol Cell. 2009 Mar 27;33(6):784-90. Epub 2009 Mar 12. Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA. Kang M, Peterson R, Feigon J. Erratum in Mol Cell. 2010 Aug 27;39(4):653-5. An explanation of the differences: J Am Chem Soc. 2011 Apr 13;133(14):5190-3. Epub 2011 Mar 16. Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics. Zhang Q, Kang M, Peterson RD, Feigon J. Cheers, Mike ----- Original Message ----- From: "Vandu Murugan" <wandumuru...@gmail.com> To: CCP4BB@JISCMAIL.AC.UK Sent: Friday, May 20, 2011 11:34:31 PM GMT -08:00 US/Canada Pacific Subject: [ccp4bb] Crystal structure and NMR structure Dear all, I would like to get some information on proteins where there is conformation/structural change between the crystal structure and solution structure of the same protein. Do anybody came across such situations? Thanks in advance.. cheers, Vandu -- Michael C. Thompson Graduate Student Biochemistry & Molecular Biology Division Department of Chemistry & Biochemistry University of California, Los Angeles mi...@chem.ucla.edu
