Posted on behalf of David Chuang, Ph.D.:
Postdoctoral Position in X-ray Crystallography is available in the Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas. The incumbent will: 1) investigate the structure and function of mitochondrial protein kinases (for references see: EMBO J. 24:1763, 2005; EMBO J. 25:5983, 2006; Structure 16:1849, 2008), and 2) work with a multi-disciplinary team comprising biochemists, synthetic chemists, pharmacologists and structural biologists to structure-based design and produce novel small-molecule inhibitors specific for these protein kinases. The inhibitors will be studied in cell culture and animal models as new strategies to metabolically target cancer, type 2 diabetes and disorders in branched-chain amino acid catabolism. Applicants must have a Ph.D. degree with training and first-author publications in X-ray crystallography. Send CV with cover letter and names of three references to Dr. David Chuang [email protected]. UT Southwestern is an Equal Opportunity, Affirmative Action employer.
