*Postdoc position at the MRC-National Institute for Medical Research, London, UK*

**Applications are invited for a Postdoctoral position in the Division of Molecular Structure in the group of Katrin Rittinger. The position is aimed at the structural and mechanistic characterisation of proteins that are part of the ubiquitin transfer cascade. In particular, we are interested in determining how different types of poly-ubiquitin chains are synthesized and how their linkage type determines specificity in signalling.

The successful candidate will have arelevant PhD or be in the final stages of completing their PhD in biochemistry, biophysics or structural biology.Knowledge of basic molecular biology techniques and protein expression is essential. Previous experience in X-ray crystallography, enzyme kinetics and the use of biophysical techniques for the characterisation of protein complexes would be an advantage.

Applicants should be able to learn quickly, have an interest in collaborative work, be able to communicate scientific ideas effectively and have a proven publication record.

//Informal inquires should be addressed to Dr. Katrin Rittinger via e-mail [email protected] <mailto:[email protected]>

Salary range is from £27,513 per annum inclusive of London Allowance.MRC final salary Pension Scheme is available. This is a three year fixed term position.

*Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at **https://ext.ssc.rcuk.ac.uk* <https://ext.ssc.rcuk.ac.uk/>*and complete an online application form. Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867003, Please quote reference number IRC23308. **Closing date: 7th July 2011*

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