Dear ccp4bb,

Apologies for the off-topic posting, but I would be grateful if you could bring the availability of the PhD studentship detailed below to anyone who may be interested.

Funding restrictions dictate that the position is open to EU nationals who are normally domiciled in the UK.

Many thanks

Jim Spencer

A PhD position will shortly be available (from 1st October 2011 or as soon as possible thereafter) in the laboratory of Dr J. Spencer in the School of Cellular and Molecular Medicine, University of Bristol, UK. The student will use a variety of structural (X-ray crystallography) and biophysical (enzyme inhibition assays, fluorescence and isothermal titration calorimetry) methods to study the interaction of metallo-beta-lactamases (MBLs) with a range of small molecule inhibitors. MBLs protect host bacteria, particularly Gram-negative species responsible for healthcare-associated infections, from almost all beta-lactam (pencillin and related) antibiotics, including carbapenems, the most effective current treatments for such infections. The studentship is funded for three years by the UK Medical Research Council and forms part of a larger collaborative network of laboratories in the UK and Canada that aims to develop new countermeasures for MBLs as a basis for improved treatments for infections by antibiotic-resistant Gram-negative bacteria. Applicants should have, or be about to obtain, a first or upper second class degree in a biomedical science (e.g. Microbiology, Biochemistry etc.) or a related discipline.

Informal enquiries are welcome to Dr. Spencer ([email protected]; (44) (0) 117 331 2084).

Applications for postgraduate study may be made on online:

http://www.bristol.ac.uk/prospectus/postgraduate/2011/intro/apply.html.

Information on postgraduate study at the University of Bristol is available at:

http://www.bristol.ac.uk/prospectus/postgraduate/2011

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Dr. James Spencer,
Lecturer in Microbiology
School of Cellular and Molecular Medicine
Medical Sciences Building
University of Bristol
University Walk
Bristol BS8 1TD
[email protected]
http://www.bristol.ac.uk/cellmolmed/staff/spencer.html
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Tel: (44) (0) 117 331 2084
Fax: (44) (0) 117 331 2091

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