If it is of moderate resolution (3 ish), uncheck automatic weighting in RefMac and constrain to 0.007-0.01. You're probably over-fitting your data.
-Joe ____________________ Joseph M. Watts, Ph.D. Research Scientist Syngenta Biotechnology, Inc.
If it is of moderate resolution (3 ish), uncheck automatic weighting in RefMac and constrain to 0.007-0.01. You're probably over-fitting your data.
-Joe ____________________ Joseph M. Watts, Ph.D. Research Scientist Syngenta Biotechnology, Inc.