Dear all
A postdoctoral position for a crystallographer/ enzymologist is
available in the Division of Molecular Structure at the NIMR
Medical Research Council
National Institute for Medical Research
Structure and mechanism of the retroviral restriction factor SAMHD1
Division of Molecular Structure
A postdoctoral fellowship is available in the laboratory of Dr Ian
Taylor to study the structre and mechanism of the recently described
retroviral restriction factor, SAMHD1. The primary focus of the
project will be to establish the relationship between the biochemical
and enzymatic properties of SAMHD1 and the mechanism of virus
restriction.
The project will be carried out in close collaboration with the
laboratory of Dr Jonathan Stoye.
Candidates should have a thorough training in the practical aspects of
structural and biochemical analysis of proteins as well as a good
understanding of enzymolgy. Enthusiasm to advance the project as well
as an understanding of retrovirology would be a significant advantage.
The successful candidate will have a relevant PhD or be in the final
stages of completing their PhD in biochemistry, biophysics or
structural biology. Knowledge of basic molecular biology techniques
and protein expression is essential. Previous experience in X-ray
crystallography, enzyme kinetics and the use of biophysical techniques
for the characterisation of protein complexes would be an advantage.
Applicants should be able to learn quickly, have an interest in
collaborative work, be able to communicate scientific ideas
effectively and have a proven publication record.
Contact Information:
Informal inquires should be addressed to Dr. Ian Taylor via e-mail
[email protected]
Situated in Mill Hill, North West London, the MRC National Institute
for Medical Research is the largest MRC institute, supporting some 70
research groups and 500 bench scientists. The Institute provides
excellent training for researchers in a multi-disciplinary environment
and is equipped with state of the art facilities, including genetic
modification of mice, imaging, histology, and high throughput
sequencing.
Salary range is from £27,513 per annum inclusive of London Allowance.
MRC final salary Pension Scheme is available.
Applications are handled by the RCUK Shared Services Centre; to apply
please visit our job board at https://ext.ssc.rcuk.ac.uk and complete
an online application form. Applicants who would like to receive this
advert in an alternative format (e.g. large print, Braille, audio or
hard copy), or who are unable to apply online should contact us by
telephone on 01793 867003, Please quote reference number IRC26991.
Closing date: 7 September 2011
Interview date: 20 – 22 September 2011
The MRC is an Equal Opportunities Employer
Final appointments will be subject to a pre employment screening
