Postdoctoral Fellow in Ubiquitin Biology Description:
The Structural Genomics Consortium (SGC), Toronto, is seeking a talented and self-motivated PhD scientist to study the structure, function, and mechanism of HECT-type E3 ubiquitin ligases and ubiquitin-specific proteases. The successful candidate will utilize the established high-throughput structural biology (HTSB) platform in SGC and biochemical/biophysical techniques to investigate the specificity and regulation of the enzymes. S/he is expected to make primary contribution to publications in high quality peer reviewed journals. This position will be co-supervised by Prof. Cheryl Arrowsmith, and is available immediately and open until filled. About SGC: SGC is a research organization focusing on understanding the structure and function of proteins of medical relevance and generating corresponding biological and chemical reagents to study their cellular functions and potential as therapeutic targets. SGC is jointly funded by public funding agencies and industry. The HTSB platform in SGC provides access to high capacity prokaryotic and eukaryotic expression systems, state-of-the-art protein purification and crystallography facilities, and is supported by cloning, crystallography, biophysics, chemistry, and antibody engineering teams. Universityof Toronto: SGC provides a stimulating and friendly working environment in the heart of the University of Toronto and its affiliated hospital research institutes. Together these institutions comprise one of the largest and most productive centers of biomedical research in North America. The city of Toronto is ranked fourth in the World’s Most Liveable Cities, and second in Cities of Opportunity in 2011. Qualifications: The candidate requires a PhD in biochemistry, biophysics, or a related area with practical experience of protein purification. 0-2 years postdoctoral experience is preferred. Knowledge in structural biology (X-ray crystallography or NMR) is an asset but not required. Contact: Interested individuals please send a current CV (including contacts of three referees) and a cover letter to Dr.Yufeng Tong at [email protected] with the term “ubiquitin” in the subject line. Yufeng Tong, Ph.D. SGC Fellow, Team Leader of Ubiquitin Biology Structural Genomics Consortium, University of Toronto Tel: +1-416-946-3874 Fax: +1-416-946-0588
