Re: [ccp4bb] Cadmium sites and co-ordinations in structure

[Roger Rowlett]

Cadmium(II) prefers softer Lewis bases (e.g. thiolates and imidazole ligands more than carboxylates) and is  commonly found in a four-coordinate environment, similar to zinc(II). Cheers, -- Roger S. Rowlett Gordon & Dorothy Kline Professor Department of Chemistry Colgate University 13 Oak Drive Hamilton, NY 13346 tel: (315)-228-7245 ofc: (315)-228-7395 fax: (315)-228-7935 email: rrowl...@colgate.edu On 8/26/2011 10:46 AM, Boaz Shaanan wrote: Hi, I recall seeing some (old) ConA structures with Cadmium substituting for one of the native metals (Ca+2 or Mn+2). They must be in the PDB database. Boaz Boaz Shaanan, Ph.D. Dept. of Life Sciences Ben-Gurion University of the Negev Beer-Sheva 84105 Israel E-mail: bshaa...@bgu.ac.il Phone: 972-8-647-2220 Skype: boaz.shaanan Fax: 972-8-647-2992 or 972-8-646-1710 ________________________________________ From: CCP4 bulletin board [CCP4BB@JISCMAIL.AC.UK] on behalf of Sandeep [s.talapa...@beatson.gla.ac.uk] Sent: Friday, August 26, 2011 4:54 PM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Cadmium sites and co-ordinations in structure Hi, I crystallised a protein in the presence of Calcium, Cobalt, and Cadmium and determined its structure. It turns out that I see several metal sites in the structure, mostly cadmiums. Is there any information published (preferably a review) which summarises data on cadmium sites in proteins such as for example the possible coordination numbers of cadmium, distances, type of side chains found to coordinate with cadmium, etc.? I could extract all this from the PDB, but a nice review would be simpler to start with. Thank you in advance for your help Sandeep