Applications are invited for a postdoctoral position to work on the development of high throughput techniques for membrane protein structure determination in collaboration with the Canadian Light Source researches Drs. P. Grochulski and M. Fodje. The Canadian Macromolecular Crystallography Facility (http://cmcf.lightsource.ca/), where the fellow will work part of the time is located in Saskatoon a short drive away. Lemieux lab is involved in the structure determination of membrane protein targets including Rhomboid membrane embedded enzymes. These proteases are critical in cell signaling pathways and have been linked to human disorders such as hereditary blindness and breast cancer. We seek an enthusiastic candidate *experienced in macromolecular crystallography.* Experience with membrane protein biochemistry would be an asset. In addition, the successful candidate should be well-versed in one or more of the following areas: molecular biology, protein purification, crystallization, membrane protein & lipid biochemistry or automation.
This is an opportunity to join a lab experienced in the expression and crystallization of membrane proteins (See *PNAS *(2007) 104(3):750-4, and *Science, *(2003)*. *301:616-620). Our department provides interaction with numerous crystallographers. In addition, the membrane protein research group provides a dedicated forum for membrane protein research at the University of Alberta (http://www.mprg.med.ualberta.ca/index.php).The University of Alberta, located in Edmonton, Alberta (Canada), is home to a large and interactive community of biomedical scientists http://www.med.ualberta.ca/; support and facilities for structural biology are excellent. Edmonton, having a population of over 1 million, offers a cosmopolitan environment with world class performing arts, sports, culinary and recreational opportunities. In addition, the city’s proximity to the Rocky Mountains including the towns of Jasper and Banff is an additional bonus. Salary is commensurate with training and experience at the CIHR standard rates. A medical and dental benefit package is included with salary. The University of Alberta hires on the basis of merit. We are committed to the principle of equity in employment. We welcome diversity and encourage applications from all qualified women and men, including persons with disabilities, members of visible minorities, and Aboriginal persons. The records arising from this competition will be managed in accordance with provisions of the Alberta Freedom of Information and Protection of Privacy Act (FOIPP). Please direct CV's or inquiries to Dr. M. Joanne Lemieux at the following email address: joanne.lemi...@ualberta.ca <joanne.lemi...@ualberta.ca>. -- ********************************** M. Joanne Lemieux, Ph.D. Assistant Professor, Canada Research Chair in Membrane Protein Structure and Function; AIHS Scholar Department of Biochemistry, Faculty of Medicine & Dentistry, University of Alberta Medical Sciences Bldg. Office 4-53 Lab 4-51 University of Alberta Edmonton AB, T6G 2H7 office phone: 780-492-3586 lab phone: 780-492-3465 fax: 780-492-0886 Lab web page: http://www.biochem.ualberta.ca/faculty_detail.php?id=39# http://www2.biochem.ualberta.ca/LemieuxLab Membrane protein disease research group: http://www.mprg.med.ualberta.ca/index.php CONFIDENTIALITY WARNING This communication is intended for the use of the recipient to which it is addressed, and may contain confidential, personal, and/or privileged information. Please contact me immediately if you are not the intended recipient of this communication, and do not copy, distribute, or take action relying on it. Any communication received in error, or subsequent reply, should be deleted or destroyed.
