Dear all,

A postdoc position is available in Stephen Curry's lab at Imperial College 
London.
See: http://www.jobs.ac.uk/job/ADK187/research-associate/
Peter

Research Associate
Imperial College London - Division of Cell & Molecular Biology, Faculty of 
Natural Sciences

Salary: £31,300 - £39,920 per annum

A Research Associate post is available to join Prof Stephen Curry's research 
group on the structural biology of enzymes from RNA viruses, within the 
Division of Cell & Molecular Biology. The position is based at the South 
Kensington Campus of Imperial College London.

Our recent work has established new breakthroughs in the structural and 
functional analyses of proteases, polymerases and helicases from picornaviruses 
and caliciviruses (see http://www.bio.ph.ic.ac.uk/~scurry/ for publications. We 
are now looking to take this work forward in exciting new directions.

The post will involve taking on the role of lead researcher on a project to 
investigate structural and functional aspects of enzymes from RNA viruses. The 
project is of a highly multi-disciplinary nature and will likely involve 
protein structure determination by protein crystallography and NMR (the latter 
in collaboration with Prof Matthews' group).

The successful candidate should have or be about to receive a PhD degree in a 
relevant subject, preferably structure determination by protein 
crystallography, or have equivalent level of professional qualifications and 
experience. Previous experience of working in a structural biology research 
environment and knowledge and experience of X-ray data collection at 
synchrotron sources, structure determination of macromolecules by X-ray 
crystallography, cloning, over-expression and purification of proteins and 
preparation and handling of recombinant proteins are essential.

A good understanding of protein over-expression in E. coli (with and without 
minimal media), and requirements of sample preparation for NMR methods are 
desirable. Use of the Linux operating system, and data processing with the CCP4 
package, CNS or Phenix refinement and model building in O/coot would be also an 
advantage.

You must have demonstrable ability to learn new techniques, to work 
independently and with imagination.

This is a fixed term position available immediately for up to 3 years.

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select "Job Search" then enter 
the job title or vacancy reference number including spaces NS 2011 200 DPN into 
"Keywords"). Please complete and upload an application form as directed, 
attaching a curriculum vitae, a cover letter and the name and contact details 
of two referees.  For informal enquiries please contact Dr Stephen Curry via 
email [email protected].

Alternatively, if you are unable to apply online, please contact Hafiza Bibi by 
email [email protected] to request an application form.

Closing date: 2 November 2011

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