[Please note: I am posting this to ccp4bb on behalf of Prof. Dale Wigley and all communication should be directed to him.]
Staff Scientist and Post-doctoral positions in Structural Biology and Biochemistry/Enzymology Following the award of a Wellcome Trust Senior Investigator Award to Professor Dale Wigley, the Institute of Cancer Research is seeking to appoint a Staff Scientist and two post-doctoral fellows on a programme to study chromatin modifying complexes involved in DNA damage repair and cancer. Current projects include the INO80 remodelling complex, the Swr1 histone exchange complex and Tip60 acetylation/exchange complex. The successful applicants will join a multi-disciplinary team of scientists with varied expertise working on DNA repair processes from biochemistry to structural studies using both crystallography and electron microscopy. The Staff Scientist position will require a person with extensive (5-8 years) post-doctoral experience of X-ray crystallography and/or single particle electron microscopy together with a sound knowledge of molecular biology/biochemistry. Post-doctoral candidates will have experience in either the biochemistry of protein:nucleic acid interactions or structural biology (electron microscopy or X-ray crystallography), preferably at a post-doctoral level. The Division of Structural Biology has managed facilities for protein crystallography (Bruker Microstar with CCD detector, crystallisation robots), cryo-electron microscopy (FEI Tecnai F20 and T12), and protein production with expertise in multi-subunit expression (insect cell, yeast and bacterial expression including a 60 L fermentor). The Division is also well equipped with equipment for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering). The Staff Scientist will be appointed for 5 years in the first instance within the salary range £37477 to £44336 p.a. and the post-doctoral applicants will be appointed for 3 years initially within the scale £29695 to £37476 p.a. Applications can be made to Prof. Dale Wigley ([email protected]<mailto:[email protected]>). -- Dr Chris Richardson :: Sysadmin, structural biology, icr.ac.uk<http://icr.ac.uk> The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP. This e-mail message is confidential and for use by the addressee only. If the message is received by anyone other than the addressee, please return the message to the sender by replying to it and then delete the message from your computer and network.
