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Dear Jacob,

what do you mean by 'molecular transform'? Would you like to visualise
the summed structure factors from the atoms inside the unit cell?
- - What pattern are you talking about/ what pattern do you expect?
- - What benefit do you expect from seeing the phases? What you can
physically observe on the detector are the intensities - the concept of
'phases' is just a mathematical notion to explain the intensities in
terms of interference from single waves and an atomistic model inside
the crystal.
- - What makes you think the pattern from a larger molecule would have a
more complex pattern?

Cheers,
Tim

On 01/10/2012 12:13 AM, Jacob Keller wrote:
> I like that animation a lot, as it shows the gradual nature of the
> lattice effect, but it is not exactly what I am looking for. I am
> actually just curious what the pattern behind the spots looks like for
> various molecules, and would like to see an image of that in various
> orientations. I guess one way to put it is that I would like to see
> what the 1.5-2 Ang diffraction pattern would be for a single,
> radiation-damage-impervious protein or RNA/DNA molecule given enough
> x-rays and time.
> 
> Would the intensities-based transform image be much less complicated
> than the phases-based one?
> 
> Would larger molecules have more complex patterns, corresponding to
> the amount of information in their structures?
> 
> JPK
> 
> 
> 
> On Fri, Jan 6, 2012 at 6:23 PM, James M Holton <[email protected]> wrote:
>> You mean something like the animation at the top of this web page?
>>
>> http://bl831.als.lbl.gov/~jamesh/fastBragg/
>>
>> This program is a relative of nearBragg, which Dale already mentioned.
>>
>> -James Holton
>> MAD Scientist
>>
>> On Jan 6, 2012, at 5:44 PM, Jacob Keller <[email protected]> 
>> wrote:
>>
>>> Actually, as a way to make this type of figure, I think there are
>>> programs which output simulated diffraction images, so perhaps I could
>>> just input a .pdb file with some really huge (fake) cell parameters
>>> (10,000 Ang?), and then the resulting spots would be really close
>>> together and approximate the continuous molecular transform. I think
>>> this would amount to the same thing as the molecular transform of the
>>> model itself--am I right?
>>>
>>> Does anyone know which software outputs simulated diffraction images?
>>>
>>> Jacob
>>>
>>> On Fri, Jan 6, 2012 at 10:25 AM, Jacob Keller
>>> <[email protected]> wrote:
>>>> Dear Crystallographers,
>>>>
>>>> has anyone come across a figure showing a normal diffraction image,
>>>> and then next to it the equivalent molecular transform, perhaps with
>>>> one image as phases and one as amplitudes? Seems like it would be a
>>>> very instructional slide to have to explain how crystallography works
>>>> (I know about Kevin Cowtan's ducks and cats--I was looking for
>>>> approximately the same but from protein or NA molecules.) I don't
>>>> think I have ever seen an actual molecular transform of a protein or
>>>> NA molecule.
>>>>
>>>> All the best,
>>>>
>>>> Jacob
>>>>
>>>> --
>>>> *******************************************
>>>> Jacob Pearson Keller
>>>> Northwestern University
>>>> Medical Scientist Training Program
>>>> email: [email protected]
>>>> *******************************************
>>>
>>>
>>>
>>> --
>>> *******************************************
>>> Jacob Pearson Keller
>>> Northwestern University
>>> Medical Scientist Training Program
>>> email: [email protected]
>>> *******************************************
> 
> 
> 

- -- 
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen

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