On 11 Jan 2012, at 11:36, Thomas Womack wrote:

> 
> On 11 Jan 2012, at 02:13, Artem Evdokimov wrote:
> 
>> There are two sides to this qustion: the scientific one is actually easier 
>> to answer in generic terms - but I also would like to point out the very 
>> recent example of a mystery that required very high resoluton (and 
>> orthogonal techniques) to answer, namely the puzzle of the light atom in the 
>> center of the mofe nitrogenase protein. Highly recommended reading.
>> 
> That does sound interesting: could you give a reference?  I can find various 
> papers about small slices of the puzzle, but not a review article.

http://www.sciencemag.org/content/334/6058/974.full is the work using 
orthogonal techniques to figure out which the light atom actually was, with a 
discussion at
http://www.sciencemag.org/content/334/6058/914.full 

The high-resolution structure that revealed that there was a light atom there 
is from 2002: http://www.sciencemag.org/content/297/5587/1696.full with 
discussion at http://www.sciencemag.org/content/297/5587/1654.full

Tom

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