A Postdoctoral Fellowship is available to join the BM14<http://www.bm14.eu/>MAD MX beamline team
at the ESRF, Grenoble, France. EMBL Grenoble operates the ESRF BM14 beamline under a MoU with the Department of Biotechnology of India (DBT) and thus provides access to both European and Indian MX communities. We are seeking to recruit a motivated postdoctoral fellow experienced with synchrotron data collection and phasing methods to support BM14 users. On the in-house research side, the successful candidate will be offered to join the structural studies of Toxoplasma gondii epigenetic machinery that we conduct in close collaboration with Dr Hakimi, (Grenoble Medical University). His team has shown that the parasite possesses a sophisticated ‘histone code’ rivaling those described in higher eukaryotic cells (Sautel et al. MCB, 2007; Bougdour et al. J. Exp. Med, 2009). Several protein targets with potential relevance to the T. gondii disease mechanisms have been highlighted. These proteins offer exciting opportunities for novel discoveries because of their lack of prior characterization. EMBL Grenoble Outstation is embedded in the Grenoble Partnership for Structural Biology (PSB), which is a unique environment for structural biology as it provides access to state-of-the-art facilities for protein production, biophysical characterisation, crystallisation and structure determination (ESRF synchrotron, NMR, EM). Qualifications and Experience Candidates should have a PhD and a record of successfully working on challenging structural biology problems. A strong biophysics background is mandatory. The ideal candidate must possess sufficient biochemical experience in cloning, protein expression and purification, and crystallization. Application Instructions: please apply online through www.embl.org/jobs. Thank you Hassan Belrhali (belrhali at embl.fr)
