Hi,

I've given a couple talks/demos to HS students.  As much as I love enzymes, I 
found it more effective to show structures of proteins binding to other 
biological molecules (not just other proteins).  I typically show 
phosphatidylinositol binding protein (PITP) bound to phosphatidylcholine, 
simply because that is a structure I solved and am comfortable with.  I think 
DNA binding proteins would also be effective.  p53 might be a good candidate, 
especially because of its association with cancer - that will get their 
attention.

I used pymol, it was easy to install on the teachers computer, then they could 
easily use it after I left.

Regards,
Marilyn

Marilyn D. Yoder
Division of Cell Biology & Biophysics
School of Biological Sciences
University of Missouri-Kansas City
5007 Rockhill Rd.
Kansas City, MO 64110
Phone: 816-235-1986

From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of James 
Whittle
Sent: Friday, January 20, 2012 3:41 PM
To: [email protected]
Subject: [ccp4bb] protein structure for high schoolers

Hi-

I am trying to help my former chemistry teacher set up a demonstration of 
protein structure for her class. I'd like to include electron density maps, and 
maybe show an enzyme active site. Are there suggestions from the BB on the 
easiest way to do this? Would pymol be the program of choice, or is there a 
simpler program that could show electron density? Has anyone already created 
such a demonstration they could and have advice on it?

James

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