A position is available in the Department of Biochemistry for a talented 
postdoctoral structural biologist to work on a new 3 year collaborative project 
with MRC Technology focussed on protein structure-based drug discovery and 
development. The scientist will work in the groups of Prof. Mark Carr and Dr 
Richard Bayliss, with a combination of NMR spectroscopy and X-ray 
crystallography used to determine the structures of proteins targeted by MRC 
Technology drug discovery programmes and to characterise their interactions 
with candidate drugs. The proposed work will involve close interactions with 
experienced research scientists at MRC Technology. The Department of 
Biochemistry is superbly equipped for all aspects of NMR spectroscopy and X-ray 
crystallography based structural biology, with excellent supporting facilities 
for recombinant protein expression and purification. The research fellow 
position will be supported by a dedicated, part-time (60%) protein biochemistry 
research assistant.

The successful postdoctoral research fellow will have a proven track record in 
either NMR spectroscopy or X-ray crystallography based structural biology, with 
some experience in NMR-based approaches desirable. A clear willingness and 
desire to apply either approach to solve protein structures is essential. A 
strong interest in knowledge-based drug discovery is also essential for the 
position. The ability and willingness to travel to meetings with collaborators 
and to use off-campus research facilities is essential. Good communication and 
presentation skills are also a pre-requisite.

Informal enquiries may be made to Prof. Mark Carr, Tel: +44 (0)116 229 7075, 
E.mail: [email protected], or to Dr Richard Bayliss, Tel +44 (0)116 229 7100, 
E.mail [email protected]. Applications must be made through the University 
vacancies website, reference MBP00560.

http://www2.le.ac.uk/offices/personnel/job-vacancies/?newms=jj&id=73578&newlang=1

Closing date for applications is midnight on 11th March 2012

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Dr Richard Bayliss, Reader in Structural Biology
Department of Biochemistry
Henry Wellcome Building
University of Leicester
Lancaster Road, Leicester
LE2 9HN

Tel: 0116 2297100
Web: http://www2.le.ac.uk/departments/biochemistry/staff/richard-bayliss/

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