A Postdoctoral position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institute of Neurological Disorders and Stroke to study the structure and mechanism of tubulin post-translational modification enzymes. The Roll-Mecak Laboratory is interested in understanding the interplay between microtubules and their regulators and how tubulin post- translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011. Nature Struct. & Molec. Biol. 8(11): 1250-8; Roll-Mecak, A. and Vale, R.D. 2008. Nature, 451(7176):363-7; Roll-Mecak, A. and McNally, F.J. 2010. Curr. Opin. Cell Biol., 22(1):96-103). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques. We value a vibrant and collaborative environment where lab members share ideas, reagents and expertise and want to work on fundamental problems in cytoskeletal biology.

The Roll-Mecak lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda. The NIH has a long tradition of research excellence in cytoskeletal biology and offers a stimulating environment for postdoctoral fellows interested in interdisciplinary training in structural biology and biophysics. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF and confocal microscopes. For more information, please visit: http://intra.ninds.nih.gov/rm_lab/

The position will be fully funded by the NIH, and is available immediately. We are looking for candidates who wish to work on structure-function studies of microtubule regulators and have a strong background in at least two of these areas: protein biochemistry, structural biology or cell biology.

Other details: candidates should preferably have less than 2 years of postdoctoral experience. Please send a CV, a one-page research experience summary, and contact information of three references to [email protected] Please write “Postdoctoral application” in the subject header.

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