Five Postdoctoral Research Associates in Molecular Biology and Macromolecular Crystallography
Reference Code ORNL12-87-BSMD Eligibility Requirements Degree: Currently pursuing a Doctoral Degree or have received this Degree within 60 months. Description The Neutron Sciences Directorate (NScD) at Oak Ridge National Laboratory operates the High Flux Isotope Reactor (HFIR), the United States highest flux reactor based neutron source, and the Spallation Neutron Source (SNS), the world's most intense pulsed accelerator based neutron source. Together these facilities operate 24 instruments for neutron scattering research, each year carrying out 1000 experiments in the physical, chemical, materials, biological and medical sciences for 2000 visiting scientists. HFIR also provides unique facilities for isotope production and neutron irradiation. To learn more about Neutron Sciences at ORNL go to: http://neutrons.ornl.gov. The Biology and Soft Matter Division at Oak Ridge National Laboratory (ORNL) invites applications for up to 5 positions for biochemist/molecular biologists and macromolecular crystallographers. The successful candidates will carry out research investigating the structure and function of several biological systems, including human cAMP dependent protein kinases, plant cellulose synthase complexes, and bioenergy related enzymes involved in isomerization and epimerization reactions. These projects involve multi-task, multi-disciplinary efforts involving molecular biology, protein crystallography, small–angle scattering, rational design using computer modeling techniques, and enzymology. The positions represent an excellent opportunity for researchers to develop their careers and interact with leading scientists from around the world. Qualifications A Ph.D. degree in structural biology or a related field is required. The candidates should have a proven track record in molecular biology techniques including, plasmid-based heterologous protein expression, protein purification, protein crystallographic data collection, and structure determination and refinement. Expertise in isotopic labeling, eukaryotic expression systems, and biofermentation would be a distinct advantage. The candidates should be self-motivated, have good interpersonal, communication and presentational skills and demonstrated ability to interact effectively with staff at all levels and to work within a multi-disciplinary team. Required disciplines: Structural Biology, Biochemistry, Molecular Biology. Questions regarding these positions can be directed to Dr. Hugh O’Neill ([email protected]); Dr. William Heller ([email protected]); Dr Leighton Coates ([email protected]) or Dr. Paul Langan ([email protected]). Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Number of Openings 5 Program Postgraduate Division Biology and Soft Matter Academic Levels Postdoctoral
