On 11/03/2012 12:06 PM, Xiaodi Yu wrote:
how common it is that electrostatic interactions are involved in intra-molecular interactions, particularly in intrinsically disordered proteins?
It's impossible to answer your question unless you define what you mean by "degree of commonality".

If you are asking if salt bridges happen - yes, they do.  All the time.

On the other hand, it must be impossible to conclude anything with certainty about details of interactions within "intrinsically disordered proteins". It's impossible to determine their structure because they are, well, disordered. But I know of no law of physics that would prevent electrostatic interactions in such molecules.



Oh, suddenly throwing a giraffe into a volcano to make water is crazy?
                                                Julian, King of Lemurs

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